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10
2019 - 11 - 01
据《世界阿尔茨海默症2018年报告》显示,每3秒钟,全球就有一位痴呆症患者产生。全球目前至少有5000万的痴呆患者。在中国,目前约有1000万阿尔茨海默症患者,预计到2050年,患者数将超过4000万人,比加拿大的总人口还要多。因此,理解这种疾病的发病原因比以往任何时候都更加迫切。此前有许多研究已经发现了一些增加罹患痴呆症风险的因素。有些因素是无法阻止的,如衰老。然而,其他潜在风险因素是有可能避免的,比如吸烟与饮酒。确定这些风险因素非常重要,因为它们有助于预防或延缓痴呆症的发生。近日,发表在JAMA Network Open上的一篇研究,来自美国哈佛大学T.H.Chan公共卫生学院的研究人员设计了一项研究以寻找痴呆症与饮酒之间的联系。尽管已有关于饮酒与痴呆症的相关研究,但研究的科学性还有所欠缺。例如,在之前的一项研究中,研究人员计算了每年的日平均饮酒量。但是以这种方式计算的每日平均饮酒量会忽略酒精含量和饮酒频率的细微差别。这一点非常重要。例如,每周有一天喝7杯啤酒可能会产生不同于每晚喝1杯啤酒的影响,尽管消耗的酒精量是一样的。另一项研究的作者得出结论,中年酗酒会增加患痴呆症的风险。然而,目前还不清楚经常性的少量饮酒是否有同样的影响。其他关于酒精、痴呆症风险、载脂蛋白E4(APOE E4)之间关联的研究使这一问题的答案更加复杂。这种基因变异与患阿尔茨海默症的风险增加有关。较早的一项研...
11
2019 - 02 - 13
日前,《分子植物》(Molecular Plant)在线发表了中国农业科学院油料作物研究所王汉中院士团队最新成果。该团队在国际上首次成功克隆了农作物种子性状的第一个细胞质调控基因 orf188,并揭示了该基因调控油菜种子高含油量的作用机制。该成果为油菜高含油量育种提供了新途径,为育种过程中杂交母本的选择提供了理论支撑,对于农作物不同类型细胞质的应用具有重要的指导意义。含油量是油菜产油量最重要的构成因子之一,随着现代育种对含油量潜力的不断挖掘,提高品种的含油量越来越困难。该团队在油菜含油量遗传研究的基础上,从细胞质效应着手对含油量母体调控新机制研究取得突破,筛选到两个对含油量具有极显著细胞质正负效应的品种,鉴定出特异基因 orf188 控制细胞质的含油量正效应,过表达该基因可以大幅度提升含油量。研究表明,orf188 为 nap(nap-like)型油菜品种所特有基因,是一个新近进化形成的嵌合基因。该团队十余年来围绕油菜种子性状的母体调控进行系统研究,此次对细胞质基因调控种子含油量机理的揭示,是该团队继发现角果皮发育调控种子粒重和含油量之后发现的又一条母体调控新途径,进一步丰富和完善了种子性状的母体调控理论,也为其他农作物性状细胞质效应的解析提供了借鉴。相关论文信息:DOI:10.1016/j.molp.2019.01.012来源:中国科学报转载:生物360
12
2019 - 06 - 14
随着技术飞速发展、医学数据的持续扩增以及硬件设备的不断提升,人工智能和医疗的结合方式越来越多样化。目前AI在医疗领域中的落地的应用场景主要有医学影像、智能诊疗、智能导诊、智能语音、健康管理、病例分析、医院管理、新药研发和医疗机器人等,其中在医学影像中的应用最为广泛。一、影像医学发展现状医学影像是医生完成诊断的主要依据,通过对影像的分析和比较,从而完成有依据的诊断。但是在实际过程中,往往会存在以下问题:(1)影像学诊断人才资源紧缺。医疗机构普遍缺乏高水平的影像医师,在疾病诊断时往往会发生同病异影,异病同影等情况。(2)传统定性分析存在诊断误差。医生普遍擅长定性分析,很多微小的定量变化无法通过肉眼判断,很难做到定量分析。(3)医生阅片时间长。目前的影像呈现方式为数据和图像,而不是最有效的信息,很大程度上限制了医生的人工阅片速度。二、AI+医学影像助力疾病诊断通过引入人工智能可有效解决部分问题,目前人工智能在医学影像领域的应用方向主要以下几类:1. 影像设备的图像重建AI可以通过算法的图像映射技术,将采集的少量信号恢复出与全采样图像同样质量的图像,而且使用图像重建技术,可以由低剂量的CT和PET图像重建得到高剂量质量图像。这样在满足临床诊断需求的同时,还能够降低辐射的风险。2. 智能辅助诊断疾病(1)智能辅助诊断肺部疾病国内应用AI+CT影像最为成熟的领域在肺结节的识别上。AI能够有效识...
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时间: 2019 - 04 - 12
描述All EVOS® fluorescence imaging systems and the Countess® II FL Automated Cell Counter contain our unique, proprietary LED light cubes. This world-leading light engine outputs remarkable intensity over a short light path that delivers superior fluorophore excitation. Each cube contains an LED, condensing optics, and hard-coated filters. EVOS® light cubes are user-changeable and automatically recognized by the system. The RFP light cube is ideal for use with Alexa Fluor® ...
型号:
时间: 2019 - 04 - 12
描述All EVOS® fluorescence imaging systems and the Countess® II FL Automated Cell Counter contain our unique, proprietary LED light cubes. This world-leading light engine outputs remarkable intensity over a short light path that delivers superior fluorophore excitation. Each cube contains an LED, condensing optics, and hard-coated filters. EVOS® light cubes are user-changeable and automatically recognized by the system. The GFP light cube is ideal for use with Alexa Fluor® ...
型号:
时间: 2019 - 04 - 12
描述All EVOS® fluorescence imaging systems and the Countess® II FL Automated Cell Counter contain our unique, proprietary LED light cubes. This world-leading light engine outputs remarkable intensity over a short light path that delivers superior fluorophore excitation. Each cube contains an LED, condensing optics, and hard-coated filters. EVOS® light cubes are user-changeable and automatically recognized by the system. The DAPI light cube is ideal for use with Acridine, Alexa F...
型号:
时间: 2019 - 04 - 12
描述This power cord is for use with EVOS® XL, FL , FL Color, and FL Auto systems in countries with Type I power plugs. The Type I electrical plug is mainly used in Australia and New Zealand, but is also used in China and parts of Asia, South America, and Africa.
型号:
时间: 2019 - 04 - 11
描述This achromat objective is ideal for general applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. This is also a phase-contrast objective, making it useful for hard-to-see, translucent speciments. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnificati...
型号:
时间: 2019 - 04 - 11
描述This achromat objective is ideal for general applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. This is also a phase-contrast objective, making it useful for hard-to-see, translucent speciments. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnificati...
型号:
时间: 2019 - 04 - 11
描述This achromat objective is ideal for general applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. This is also a phase-contrast objective, making it useful for hard-to-see, translucent speciments. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnificati...
型号:
时间: 2019 - 04 - 11
描述This fluorite objective is ideal for fluorescence and demanding transmitted-light applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of t...
型号:
时间: 2019 - 04 - 11
描述This fluorite objective is ideal for fluorescence and demanding transmitted-light applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of t...
型号:
时间: 2019 - 04 - 11
描述This fluorite objective is ideal for fluorescence and demanding transmitted-light applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of t...
型号:
时间: 2019 - 04 - 11
用途在基础研究领域用于微观物质的观察,观察其形态及所在位置。利用光学原理,对各类组织或细胞切片或各种培养容器内的细胞样品进行明场或相差、荧光观察,进而获取这些样品的成像图片工作原理显微镜是利用凸透镜的放大成像原理,将人眼不能分辨的微小物体通过内置的物镜放大到人眼能分辨的尺寸、通过照相机成像,图片可实时显示于显示器上。功能EVOS M7000整合式系统集全自动成像系统和集成式软件于一体,可通过高精度、自动化移动载物台可对样品进行准确定位;全自动聚焦可方便找到目标分子。适用于各种应用领域,包括但不限于多通道荧光成像、图像无缝拼接、细胞密度分析、多位置血管扫描和动态图像拍摄。具备多种高级功能,可对拍摄的图片进行多种分析(细胞计数、测量计算细胞直径和细胞间距离等),也可对活细胞进行延时成像拍摄。
型号:
时间: 2019 - 04 - 11
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