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4
2019 - 01 - 21
冬季流感严重危害人类健康,甚至会威胁生命,我们究竟有什么办法预防流感呢?目前,美国密歇根大学 Betsy Foxman 和同事最新研究表明,呼吸道微生物群可能与流感易感性密切相关。这项研究报告发表在 1 月 9 日出版的《美国公共科学图书馆 · 综合》杂志上。流感病毒是流感病原体,主要侵袭目标是人体呼吸道,感染上皮细胞。鼻子和喉咙的上皮细胞被复杂的细菌群落包围,因此 Betsy Foxman 和同事推测认为,这些呼吸道微生物群可能与病毒相互作用,并在人体对流感预防方面充分发挥作用。在这项研究中,研究人员对 2012—2014 年登记的 144 个尼加拉瓜家庭进行了分析,这些家庭中有一位成员被确认患有流感,包括成年人和儿童的所有家庭成员都接受为期两个星期的监测。研究人员对每个家庭进行 5 次回访信息统计,对所有家庭成员的呼吸道微生物取样,并对监控测试者进行症状日志记录。研究者使用统计模型,对每次测试的家庭成员呼吸道微生物群分类为两个不同种群类型,尽管大约一半的测试者在研究测试过程中体内微生物群类型发生了变化。接下来,研究人员将参与者微生物类型与他们流感易感性进行了对比分析。结果发现,跨年龄组的一种呼吸道微生物类型显示出对流感的易感性降低,这种微生物类型在婴儿和儿童群体中并不常见,而且与年龄较大的青少年和成年人相比,其稳定性较低。虽然微生物种群和流感易感性之间的联系在这项研究...
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2019 - 06 - 03
5月28日,南方医科大学南方医院教授李国新作为通讯作者发布了胃癌微创手术最新临床研究成果,该研究在全球范围内,首次提供了腹腔镜微创治疗局部进展期胃癌的高级别循证医学证据,揭示了腹腔镜微创手术治疗局部进展期胃癌具有确切的远期疗效与显着的微创获益。该研究在国际顶级医学期刊《美国医学会杂志》(以下简称为《JAMA》)在线发表,首次为世界胃癌治疗提供了“中国模式”,将使得更多患者受益于腹腔镜微创手术。胃癌是世界第二高发恶性肿瘤,42%的新发病例在中国,80%的患者在就诊时已发展至局部进展期,是严重影响国民健康的重大肿瘤疾病。2009年,李国新牵头组织,成立了中国腹腔镜胃肠外科研究组(CLASS),开展胃癌微创手术关键技术研究,建立了标准化手术操作方案。此多中心成员单位包括北京大学肿瘤医院(季加孚、苏向前、李子禹教授)、中国人民解放军301医院(杜晓辉教授)、复旦大学中山医院(孙益红教授)、上海交通大学瑞金医院(胡伟国教授)等。该研究组经过建立全国多中心数据库、开展系列多中心回顾性研究作为前期基础,于2012年启动了CLASS研究组的首项前瞻性临床研究(CLASS-01研究)。该研究旨在回答腹腔镜治疗局部进展期胃癌的安全性和肿瘤学疗效问题,以临床分期T2、T3或T4a的胃癌患者为研究对象,采用多中心、随机对照的试验设计,以3年无瘤生存率为主要研究终点,手术并发症、3年总生存率、术后关键恢复指...
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2019 - 11 - 01
据《世界阿尔茨海默症2018年报告》显示,每3秒钟,全球就有一位痴呆症患者产生。全球目前至少有5000万的痴呆患者。在中国,目前约有1000万阿尔茨海默症患者,预计到2050年,患者数将超过4000万人,比加拿大的总人口还要多。因此,理解这种疾病的发病原因比以往任何时候都更加迫切。此前有许多研究已经发现了一些增加罹患痴呆症风险的因素。有些因素是无法阻止的,如衰老。然而,其他潜在风险因素是有可能避免的,比如吸烟与饮酒。确定这些风险因素非常重要,因为它们有助于预防或延缓痴呆症的发生。近日,发表在JAMA Network Open上的一篇研究,来自美国哈佛大学T.H.Chan公共卫生学院的研究人员设计了一项研究以寻找痴呆症与饮酒之间的联系。尽管已有关于饮酒与痴呆症的相关研究,但研究的科学性还有所欠缺。例如,在之前的一项研究中,研究人员计算了每年的日平均饮酒量。但是以这种方式计算的每日平均饮酒量会忽略酒精含量和饮酒频率的细微差别。这一点非常重要。例如,每周有一天喝7杯啤酒可能会产生不同于每晚喝1杯啤酒的影响,尽管消耗的酒精量是一样的。另一项研究的作者得出结论,中年酗酒会增加患痴呆症的风险。然而,目前还不清楚经常性的少量饮酒是否有同样的影响。其他关于酒精、痴呆症风险、载脂蛋白E4(APOE E4)之间关联的研究使这一问题的答案更加复杂。这种基因变异与患阿尔茨海默症的风险增加有关。较早的一项研...
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时间: 2019 - 04 - 17
描述The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.• Free Attune NxT software with researcher-inspired upgrades• New green laser option for expanded utility and fluorochrome options• Simple push...
型号:
时间: 2019 - 04 - 17
描述The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.• Free Attune NxT software with researcher-inspired upgrades• New green laser option for expanded utility and fluorochrome options• Simple push...
型号:
时间: 2019 - 04 - 17
描述7-aminoactinomycin D (7-AAD) is a fluorescent intercalator that undergoes a spectral shift upon association with DNA. 7-AAD/DNA complexes can be excited by the 488 nm laser and has an emission maxima of 647 nm, making this nucleic acid stain useful for multicolor fluorescence microscopy and flow cytometry. 7-AAD appears to be generally excluded from live cells, but can be used with cells that have been fixed and permeabilized. 7-AAD has been used for cell cycle analysis by flow cytometry....
产品名称: Dynabeads™ CD45
型号:
时间: 2019 - 04 - 17
DescriptionDynabeads® CD45 are superparamagnetic beads covalently coupled to anti-human CD45 antibody that enable isolation or depletion of CD45+ leucocytes directly from whole blood, buffy coat, or MNC suspensions. Dynabeads® CD45 can also be used to enrich epithelial tumor cells. The CD45 antigen is weakly expressed on myeloid cells. To efficiently deplete or isolate all leucocytes including myeloid cells, use Dynabeads® CD15 (Cat. No. 11137D) in combination with Dynabeads®...
型号:
时间: 2019 - 04 - 15
描述This achromat objective is ideal for general applications. This is a coverslip-corrected objective that is optimized for imaging through #1.5 coverslips. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of this EVOS® objective:• Magnification: 50X• Numerical Aperture: 0.95• Working Distance:...
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时间: 2019 - 04 - 15
描述The EVOS M7000 Imaging System is a high-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system. It was developed to meet today’s expectations for image quality, user interface interactions, data generation speed and flexibility, and end-user value. The powerful and time-saving acquisition tools with enhanced autofocus algorithms and automated routines for microwell plate assays, time-lapse live cell imaging, area scanning in time lapse and Z-sta...
型号:
时间: 2019 - 04 - 15
描述The EVOS® FL Imaging System is a fully integrated, digital, inverted imaging system for four-color fluorescence and transmitted-light applications. It is powerful, yet easy-to-use and delivers high-definition images with exceptional convenience. The unique light cubes, sensitive camera, and precision-engineered optical system make the EVOS® FL system ideal for both demanding and routine fluorescence imaging applications.The EVOS® FL Imaging System offers you these important ad...
型号:
时间: 2019 - 04 - 15
描述The EVOS® Onstage Master Plate is part of the EVOS® Onstage Incubator and holds the EVOS® Onstage Vessel Holder. The EVOS® Onstage Incubator is an environmental chamber designed specifically for use with the EVOS® FL Auto Imaging System. This master plate plus vessel holder design, with vessel holders available that accommodate various types of cell culture vessels, provides flexibility in your approach to extended time-lapse imaging experiments under precisely co...
型号:
时间: 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates two 25-mL T-flasks. With ...
型号:
时间: 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates multi-well plates (dimensi...
型号:
时间: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder securely holds two 25 x 75 mm standard or chamber microscope slides and is specific for the automated stage of the EVOS® FL Auto Imaging System. It is just one of many easy-to-change vessel holders and stage plates available for this instrument plat...
型号:
时间: 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Greiner/BD T-25 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ...
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