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1
2022 - 03 - 17
来源:生物谷 2021-03-14 00:052021年3月12日讯/生物谷BIOON/--汽水是一种备受欢迎的饮料,在全世界被广泛消费。食品制造商为了丰富汽水的口味,开发了各种汽水饮品。其中不乏含糖饮料。我们知道,食品中的添加糖会给健康带来负面影响,比如增加心血管疾病、肥胖和糖尿病风险等。那么,饮用含糖汽水对乳腺癌患者的影响如何呢?近日,来自美国布法罗大学的一项新研究表明,乳腺癌患者经常饮用含糖汽水会增加全死亡的风险,尤其是因乳腺癌死亡的风险。与从不或很少喝含糖汽水的女性相比,每周喝五次或以上含糖汽水的女性其全因死亡率要高出62%,而死于乳腺癌的可能性要高出85%。相关研究结果于3月2日发表在美国癌症研究协会的Cancer Epidemiology Biomarkers & Prevention期刊上,标题为Sugar-Sweetened Soda Consumption and Total and Breast Cancer Mortality: The Western New York Exposures and Breast Cancer (WEB) Study。该研究的第一作者、布法罗大学公共卫生和健康职业学院流行病学和环境卫生系的博士生Nadia Koyratty说,关于汽水和乳腺癌的研究是非常新颖的话题。因为乳腺癌非常普遍,关于生活方式选择的建议对乳腺癌幸存者...
2
2019 - 09 - 05
2016年《消失的微生物》一书问世,肠道微生态研究走入大众视野,目前全球范围内针对微生物与肥胖、哮喘、过敏、糖尿病、肿瘤、精神类疾病的研究正逐步开展。一、肠道微生物概况人体是由自身细胞及共生的大量微生物细胞所共同组成的复杂共生生命体。目前研究认为人体肠道内聚集的微生物数目可达1012~1014个,是人体自身细胞数目的10倍,微生物包含的基因数目超过987万个,人类自身基因数只有2万个左右,是人体自身基因数目的几百倍,这些后天获得的共生菌群及其所携带的遗传及分子信息即可称为微生物组。(一)人体肠道微生物是如何建立的?有研究表明,人体在出生成长过程中,主要在两个重要的环节、以两种不同的方式实现对肠道菌群的塑造。第一个环节是在分娩过程,婴儿会从母亲产道获得健康的肠道菌群,剖腹产和孕期抗生素则会改变正常婴儿菌群的建立。另一个环节则是出生后的哺乳及断奶后的膳食干预。在女性乳腺中存在着乳酸菌等系列微生物,这些微生物在哺乳过程中进入并定植于婴儿肠道。随着哺乳期的结束,日趋丰富的膳食外源营养物质则长期调节着人体肠道微生物中的的变化。(二)肠道微生物对人体健康有何影响?肠道菌群与人体互利共生,依靠人体没有消化的食物残渣和肠道分泌的黏液和脱落的死细胞作为营养来维持很高的种群水平。活跃生长的肠道菌群会产生大量的活性物质,同时包括短链脂肪酸、维生素和抗氧化等有益健康的产物,以及神经毒素、致癌物质和免疫毒素...
3
2019 - 08 - 30
最近,《自然》杂志报道了不少关于癌症的研究。上周,学术经纬团队分享了一则癌症研究的重要突破——通过荧光标记,科学家们能够看清癌细胞如何“腐蚀”周边的健康细胞,发生转移。今天,我们又读到了一篇关于癌症转移的最新论文,它深刻揭示了癌症转移的复杂性,并提醒我们,在攻克癌症的道路上,我们还有很长的路要走……先来聊聊癌症。我们知道,癌症的发展就好像是一个熊孩子长大一样,会分成不同的阶段。在早期,癌细胞会疯狂生长,侵入和传播(invasion and dissemination)到组织内,在身体里形成肿瘤。到了晚期,癌细胞则会发生转移(metastasis),跑到身体的其他器官里落地生根,形成新的病灶。现在的医学知识告诉我们,一旦癌症发生了转移,患者的生命就岌岌可危。可是,癌细胞在一个地方长得好好的,它为啥会发生转移呢?过去的很多科学家相信,这与一种叫做E-cadherin(E-钙粘蛋白)的蛋白质有关。从功能上看,它负责把不同的细胞“粘”在一起。如果癌细胞能够减少这种钙粘蛋白的表达,就会变得更有“活动性”,也更容易发生转移。不过,科学家们也观察到了一些例外——在一种叫做“乳腺导管癌”的癌症中,发生转移的癌细胞,里头的E-钙粘蛋白含量可不少。这是为啥呢?有科学家解释说,这是因为癌细胞慢慢地又把自己“粘”回到了一起。这听起来是个合理的解释,但没有让所有人感到信服。为了寻找其他原因,来自美国知名的约...
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总部地址:北京市海淀区西二旗西路热力公司院内泰禾文化园二层
型号:
时间: 2021 - 11 - 05
仪器简介:KingFisher Flex基于磁棒式转移磁珠技术,最高通量每批同时处理96个样品,仅需15-40分钟(根据具体样品和 程序),使您从繁琐的样品提取工作中解脱,并获得高质量的产物,为下游检测带来精确结果。规格参数:技术原理KingFisher磁棒转移磁珠技术控制模式单机独立运行;通过电脑及软件控制每批通量24/48/96温控范围室温+5~+115℃磁头类型24DW磁头、96DW磁头、96KF磁头、96PCR磁头 温度准确性±1℃,up to +80℃;±2℃,up to+115℃磁棒类型末端充磁的非拼接式一体化永磁棒温控方式软件设置,每个板位均可实现温控磁套装卸软件控制,自动装卸计算机接口USB接口或RS-232C串口适用板型KF24深孔板、KF96深孔板、KF96浅孔板、96PCR板试剂兼容性通用磁珠试剂,无品牌限制工作体积20-5,000µL/孔软件BindIt3.3.1,可免费升级提取板位8个自动化兼容可与机械臂、移液工作站等周边设备整合操作界面LCD彩色显示屏,图形化用户界面外部尺寸680x600x380mm(WxDxH)仪器...
产品名称: K3 Plus酶标仪
型号:
时间: 2019 - 05 - 23
型号:
时间: 2019 - 04 - 22
描述The LIVE/DEAD™ Fixable Green Dead Cell Stain Kit is used to determine the viability of cells prior to the fixation and permeabilization required for intracellular antibody staining or prior to elimination of biohazardous materials using formaldehyde fixation. This kit has been optimized and validated for use with a blue laser flow cytometer.• Stable—dyes are freeze dried in separate vials to maintain stability• Robust—staining pattern is the same before and after fixation• Bright signal—allows...
型号:
时间: 2019 - 04 - 18
描述This product detects the externalization of phosphatidylserine in apoptotic cells using recombinant annexin V conjugated to green-fluorescent FITC dye and dead cells using propidium iodide (PI). Propidium iodide stains necrotic cells with red fluorescence. After treatment with both probes, apoptotic cells show green fluorescence, dead cells show red and green fluorescence, and live cells show little or no fluorescence.
型号:
时间: 2019 - 04 - 18
描述SYTOX® Green nucleic acid stain is an excellent green-fluorescent nuclear and chromosome counterstain that is impermeant to live cells, making it a useful indicator of dead cells within a population.•  Impermeant to live cells•  Excitation/Emission: 504/523 nm•  Use with 488 Argon-ion laser•  Works with mammalian cells and both Gram-positive and Gram-negative bacteriaSimple Viability Determination SYTOX® Green allows quick determination of cell viability when usin...
型号:
时间: 2019 - 04 - 18
描述Premo™ FUCCI Cell Cycle Sensor is a fluorescent, two-color sensor of cell cycle progression and division in live cells. It allows accurate and sensitive cell cycle analysis of individual cells or a population of cells by fluorescence microscopy, flow cytometry, or high-content imaging.At 2 x 200 µL, this is a smaller pack size version (1/5 volume) of the popular full-size product and perfect for testing its performance in your system.The Premo™ FUCCI Cell Cycle Sensor is delivered by high...
型号:
时间: 2019 - 04 - 18
描述CountBright™ absolute counting beads are a calibrated suspension of microspheres that are brightly fluorescent across a wide range of excitation and emission wavelengths (UV to 635 nm excitation and 385-800 nm emission). CountBright™ absolute counting beads are mixed with the cell sample and assayed via flow cytometry. By comparing the ratio of bead events to cell events, absolute numbers of cells in the sample can be calculated. Because CountBright™ beads are mixed in the test sample, absolut...
型号:
时间: 2019 - 04 - 17
描述CellTrace™ CFSE Cell Proliferation Kit is used for in vitro and in vivo labeling of cells to trace multiple generations using dye dilution by flow cytometry.• Superior performance—bright, single-peak staining enables visualization of multiple generations• Long-term signal stability—well-retained in cells for several days post stain• Non-toxic—staining does not adversely effect cell health• Simple, robust staining protocolView a selection guide for all CellTrace™ Cell Proliferation Kits fo...
型号:
时间: 2019 - 04 - 17
描述CellTrace™ CFSE 细胞增殖试剂盒 (CellTrace™ CFSE Cell Proliferation Kit) 以方便的一次性瓶装形式提供用途广泛,稳定性高的细胞示踪剂。 羧基荧光素二醋酸盐琥珀酰亚胺酯,常称为 CFSE,可被动扩散进入细胞。 这种试剂没有颜色和荧光,直至细胞内的酯酶去除其醋酸盐基团,产生能发出明亮荧光的羧基荧光素琥珀酰亚胺酯。 琥珀酰亚胺酯与细胞内氨基反应,形成稳定且能用醛固定剂固定的荧光偶联物。 此试剂盒包含十份一次性瓶装的 CFSE,因此进行小规模实验时无需制备过量的易变质 CFSE 储存液。 此试剂盒还包括高质量的 DMSO(二甲基亚砜)和详细的实验方案。For Research Use Only. Not for use in diagnostic procedures.图表Suppressive capacity of isolated Treg cells.Suppressive capacity of isolated Treg cells. (A) CD4+ CD25–cells were stained with Ca...
型号:
时间: 2019 - 04 - 17
描述The Click-iT® EdU Pacific Blue™ Flow Cytometry Assay Kit provides a simplified, more robust assay for analyzing DNA replication in proliferating cells as compared to traditional BrdU methods. Newly synthesized DNA is analyzed using the 405 nm laser of the flow cytometer.• Accurate—superior results compared to BrdU assays• Fast—results in as little as 90 minutes• Economical—more assays per kitView selection guide for all Click-iT™ EdU and Click-iT™ Plus EdU assays for flow c...
型号:
时间: 2019 - 04 - 17
描述The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.• Free Attune NxT software with researcher-inspired upgrades• New green laser option for expanded utility and fluorochrome options• Simple push...
型号:
时间: 2019 - 04 - 17
描述The 2018 Attune NxT Acoustic Focusing Cytometer has expanded functionalities to drive your research forward. Designed and developed to remove common barriers associated with flow cytometry, the evolutionary capabilities of the Attune NxT flow cytometer offer adaptable optical configuration options so you can get the most out of your multicolor analysis.• Free Attune NxT software with researcher-inspired upgrades• New green laser option for expanded utility and fluorochrome options• Simple push...
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