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2021 - 05 - 31
2021年05月30日讯 /生物谷BIOON/ --目前,国外新冠肺炎疫情仍在迅速蔓延。根据百度《新型冠状病毒肺炎疫情实时大数据报告》,截止2021年05月30日19时,全球累计确诊超过1.7亿(1.7068亿)例,死亡超过354.9万例。近日,辉瑞(Pfizer)与合作伙伴BioNTech联合宣布,其COVID-19 mRNA疫苗Comirnaty(BNT162b2)在欧盟的有条件营销授权(CMA)已扩大至纳入12-15岁的青少年。在此之前,欧洲药品管理局(EMA)人用医药产品委员会(CHMP)发布积极审查意见,推荐批准Comirnaty用于这一年龄组人群。此次Comirnaty CMA适应症扩展,在欧盟所有27个成员国均有效。Comirnaty是第一个在欧盟获得授权的COVID-19疫苗,也是第一个将其CMA扩展到青少年的疫苗。Comirnaty在欧盟成员国的分发和接种,将继续根据欧盟确定的人口和各个国家的指南来实施。在美国方面,今年5月10日,FDA批准扩大Comirnaty的紧急使用授权(EUA),纳入12-15岁青少年群体。值得一提的是,Comirnaty是在美国被批准用于这一年龄组的首个COVID-19疫苗。此前,FDA已授予Comirnaty用于≥16岁人群进行主动免疫的EUA。BioNTech首席执行官兼联合创始人Ugur Sahin医学博士表示:“今天,我们在欧盟...
2
2019 - 08 - 23
2019年8月23日讯 /生物谷BIOON /——2019年6月,欧洲大部分地区遭遇了早期热浪,法国的气温达到了创纪录的46摄氏度(115华氏度)。热浪的特点是在几天几夜持续高温。它们对我们的日常生活有重要的影响--我们感到过热和疲劳。当热浪来袭时,许多政府会启动一项'热行动计划',建议受影响的人多喝水,避免剧烈运动,保持凉爽。如果不这样做,就有中暑的风险,而中暑有可能危及生命。但是,人体究竟是如何应对如此极端的温度的呢?为什么高温如此危险呢?哪些器官受到影响,什么时候情况会变得更糟?图片来源:http://cn.bing.com保持凉爽人体的核心温度通常在36到38摄氏度之间波动(97到99华氏度)。在这个温度范围内,生化反应可以正常进行,这对细胞和器官的正常功能至关重要。人类的身体也能很好地应对各种可能威胁其核心温度的环境条件。当核心温度偏离正常范围时,身体就会启动生理反应,使温度恢复正常。这种温度调节反应相当于你家的恒温器;一旦内部温度偏离理想温度,加热或冷却系统就会被激活,回到理想温度。在人体中,这个恒温器位于我们大脑的底部,一个叫做下丘脑的区域。位于我们皮肤、肌肉和其他器官的温度传感器提供的信息被分析,必要时,启动生理反应。对温度升高的第一个也是最重要的反应是通过我们身体的皮肤和四肢,如手和脚散热。我们开始产生汗液,汗液会在皮肤上蒸发,在这个过程中散热。这...
3
2019 - 08 - 09
今日,美国FDA批准罗氏(Roche)公司开发的NTRK,ROS1和ALK抑制剂Rozlytrek(entrectinib)上市,治疗携带NTRK基因融合的实体瘤患者,以及携带ROS1基因突变的非小细胞肺癌患者。这也是美国FDA批准的第三款“不限癌种”的抗癌疗法。自从去年Loxo Oncology/拜耳(Bayer)公司联合开发的TRK抑制剂Vitrakvi(larotrectinib)获批以来。“不限癌种”抗癌疗法得到了广大业界人士和患者的关注。还有哪些“不限癌种“疗法即将问世?“不限癌种“的抗癌疗法发展的前景如何?今天的这篇文章里,药明康德内容团队将结合公开资料,与读者分享这些问题的答案。“不限癌种“疗法的理论基础和面对的挑战我们知道,基因突变是驱动正常细胞癌变的关键。近年来高通量测序技术的进步,让我们获得了许多对癌症背后的分子生物学机理的洞见。基于这些洞见,我们对癌症的分类不再局限于癌症起源的组织,而是基于肿瘤细胞携带的特定基因变异。这一基于分子生物学生物标志物的分类方法加快了靶向疗法的开发,而“不限癌种“的抗癌疗法可以说是靶向疗法中比较特别的一个分支。这些靶向疗法的靶点在起源于不同组织的多种癌症中存在,而且”不限癌种“疗法能够在多种癌症类型中表现出卓越的疗效。例如去年获批的Vitrakvi在携带NTRK基因融合的患者中能够达到81%的总缓解率。而刚刚获得FDA批准的Rozl...
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产品名称:

EVOS™ 50X Oil Objective, achromat, coverslip-corrected

上市日期: 2019-04-15
产品类别: EVOS

规格

For Use With (Equipment):EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Lens Type:Plan Achromat
Magnification:50X
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:Objective Lens


  • 产品描述
  • 产品功能
  • 产品参数

描述

This achromat objective is ideal for general applications. This is a coverslip-corrected objective that is optimized for imaging through #1.5 coverslips. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.

Additional characteristics of this EVOS® objective:

• Magnification: 50X
• Numerical Aperture: 0.95
• Working Distance: 0.19
• Immersion: Oil

Image Quality
Microscope objectives may be the most important components of an optical microscope because they are responsible for primary image formation. Image quality is crucial to experimental success and a requirement for publication; EVOS® objectives afford that quality across the visible spectrum to near infrared light. This performance results from years of lens manufacture perfection. EVOS® objectives have the same or better numerical apertures as any other manufacturer's in the same class, and the broad selection means you have choices for your imaging requirements.

Objective Classes

Achromat objectives are perfect for general applications, with standard correction of color and focus.

Fluorite objectives deliver excellent resolution and are made with higher numerical apertures than achromat objectives, resulting in brighter fluorescence signal and higher contrast imaging. The higher optical quality greatly reduces optical aberrations, and corrections for color and focus are at higher levels than achromat objectives. Fluorite objectives are ideally suited for fluorescence and demanding transmitted light applications, where the higher contrast make them ideally suited for color imaging.

Apochromat objectives are manufactured to the highest levels of resolution, fluorescence brightness, and contrast; chromatic aberrations are almost eliminated. They are recommended for the most demanding applications, particularly at magnifications of 60x and above. Apochromatic objectives are the best choice for the capture of color images in white light.

Brightfield Contrast versus Phase Contrast Objectives
Brightfield is the most basic form of light microscopy and is accomplished by sample absorption of light. A higher density area in a sample will absorb more light, thus increasing contrast in those areas.

Phase contrast objectives are most useful for hard to see, translucent specimens. This method of contrast is accomplished by converting phase shifts, caused by light passing through a translucent specimen, into brightness changes (i.e., contrast).

Long Working Distance versus Coverslip-Corrected Objectives
Long working distance (LWD) objectives are optimized for use through vessels with a nominal wall thickness of 0.9-1.5 mm. This includes vessels commonly used in cell culture and cell-based assays, such as slides, cell culture dishes and flasks, microtiter well plates, etc. Coverslip-corrected objectives are optimized for use through #1.5 coverslips (thickness approximately 0.17 mm). These objectives have a higher magnification/NA ratio and provide higher resolution compared to LWD objectives.


规格

For Use With (Equipment):EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Lens Type:Plan Achromat
Magnification:50X
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:Objective Lens


规格

For Use With (Equipment):EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Lens Type:Plan Achromat
Magnification:50X
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:Objective Lens


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