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1
2018 - 05 - 18
5月18日消息,哈佛大学的创业者Rejuvenate Bio已经开始测试为犬类延长寿命的方法,如果这项技术获得成功,那么将在人类身上进行试验。公司的合创者,63岁的George Church称,如果在查理士王小猎犬身上进行的医学测试成果的话,他将在自己身上进行测试。       查理士王小猎犬通常有一种心脏上的小疾病,导致半数物种在10岁左右时会因病死去。研究人员的研究已经表明,改变单一生物体的基因能够使其寿命加倍,并且在苍蝇身上取得了成功。这项研究的目的是观察在保持物种年轻身体状态的同时延长物种寿命会带来什么样的结果。Church教授被视作 “基因编辑”领域的一位先驱者,而且也正致力于借助史前DNA复活猛犸象的研究。他的返老还童实验室将发表一份关于这项技术的报告,研究人员将对老龄化疾病(比如说心脏病和糖尿病等)相关的两种基因进行修改,从而延长啮齿动物的寿命。麻省理工学院《技术评论》去年6月获得的一份文件表明,该创业公司在塔夫茨陆军兽医学院对4只米格鲁猎犬进行了测试。虽然文件中关于这次医学实验的过程透漏的很少,但是麻省理工学院的《技术评论》杂志推测,这一过程可能需要抑制一种充当“总开关”的蛋白质。Church教授称:“我们已经在老鼠身上进行了一系列的实验,而且我们正在犬类身上进行一些实验,随后我们将在人类身上进行这项技术的实验。犬类不仅仅是接...
2
2019 - 03 - 08
1 月 28 日,国际学术期刊 Circulation Research 在线发表了中国科学院上海营养与健康研究所宗耕课题组与哈佛大学公共卫生学院营养系合作的最新研究成果 “Associations of Monounsaturated Fatty Acids from Plant and Animal Sources with Total and Cause-Specific Mortality in Two US Prospective Cohort Studies”。该研究发现较高的植物来源单不饱和脂肪酸(MUFA-Ps)摄入量与较低的总死亡率相关,而动物来源单不饱和脂肪酸(MUFA-As)的摄入则与较高死亡率相关。另外,用植物来源单不饱和脂肪酸替代饱和脂肪酸(SFAs)、精加工的碳水化合物或反式脂肪可以显著降低死亡风险。在全球范围内,心血管疾病(CVD)和癌症是造成过早死亡的最主要原因。目前,越来越多的研究表明采取健康的生活方式(如戒烟、增加体力活动和提高膳食质量等)能够有效降低过早死亡的风险。多个国家的膳食指南均强调了膳食脂肪的质量对预防慢性疾病的重要性,尤其提倡植物油及其他植物来源的脂肪摄入。例如,膳食中的多不饱和脂肪酸(PUFAs)主要来自植物,而现有的研究表明 PUFAs 能够降低心血管疾病风险和死亡率的关系。与之相比,饮食中的单不饱和脂肪酸只有一半来自植物油(尤其...
3
2019 - 07 - 05
据新华社电 美国疾病控制和预防中心研究团队发现,正在刚果(金)使用的两种试验性疗法对抗击当前的埃博拉疫情有效。7 月 9 日发表在英国《柳叶刀—传染病》杂志上的研究显示,在实验室中,抗病毒药物 Remdesivir,以及由三种抗体组成的抗埃博拉药物 ZMapp 可阻断新一轮埃博拉疫情的致病毒株在人类细胞中增长。确认抗病毒药物有效的关键之一在于找到此次疫情的致病毒株。论文第一作者、美疾控中心微生物学家劳拉 · 麦克马伦说,目前在刚果(金)试用的疗法均针对以前疫情中获取的埃博拉毒株,而埃博拉是一种核糖核酸(RNA)病毒,会不断变异,因此确定现有疗法是否对新毒株奏效至关重要。美疾控中心研究人员没有当前在刚果(金)传播的 “伊图里” 毒株样本,但他们从开源基因库中获得病毒序列数据,使用 “反向遗传学” 技术重组了毒株。这项技术有助于研究人员更多了解新毒株在埃博拉家族树中的位置,从而寻找更多潜在疗法,并测试各类新疗法的有效性,还可与未来的新毒株进行比对。研究中还发现,2014 年到 2016 年西非多国爆发埃博拉疫情期间开发的一种实验室病毒诊断方法可用于诊断 “伊图里” 毒株。(周舟)文章摘自:生物360
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产品名称:

EVOS™ 10X Objective, fluorite, LWD

上市日期: 2019-04-11
产品类别: EVOS

规格

For Use With (Equipment):EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Lens Type:Plan Fluorite
Magnification:10X
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:Objective Lens


  • 产品描述
  • 产品功能
  • 产品参数

描述

This fluorite objective is ideal for fluorescence and demanding transmitted-light applications. This is a long working distance (LWD) objective that is optimized for the imaging of slides, cell culture dishes and flasks, and microtiter plates. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.

Additional characteristics of this EVOS® objective:

• Magnification: 10X
• Numerical Aperture: 0.30
• Working Distance: 8.3 mm

Image Quality
Microscope objectives may be the most important components of an optical microscope because they are responsible for primary image formation. Image quality is crucial to experimental success and a requirement for publication; EVOS® objectives afford that quality across the visible spectrum to near infrared light. This performance results from years of lens manufacture perfection. EVOS® objectives have the same or better numerical apertures as any other manufacturer's in the same class, and the broad selection means you have choices for your imaging requirements.

Objective Classes

Achromat objectives are perfect for general applications, with standard correction of color and focus.

Fluorite objectives deliver excellent resolution and are made with higher numerical apertures than achromat objectives, resulting in brighter fluorescence signal and higher contrast imaging. The higher optical quality greatly reduces optical aberrations, and corrections for color and focus are at higher levels than achromat objectives. Fluorite objectives are ideally suited for fluorescence and demanding transmitted light applications, where the higher contrast make them ideally suited for color imaging.

Apochromat objectives are manufactured to the highest levels of resolution, fluorescence brightness, and contrast; chromatic aberrations are almost eliminated. They are recommended for the most demanding applications, particularly at magnifications of 60x and above. Apochromatic objectives are the best choice for the capture of color images in white light.

Brightfield Contrast versus Phase Contrast Objectives
Brightfield is the most basic form of light microscopy and is accomplished by sample absorption of light. A higher density area in a sample will absorb more light, thus increasing contrast in those areas.

Phase contrast objectives are most useful for hard to see, translucent specimens. This method of contrast is accomplished by converting phase shifts, caused by light passing through a translucent specimen, into brightness changes (i.e., contrast).

Long Working Distance versus Coverslip-Corrected Objectives
Long working distance (LWD) objectives are optimized for use through vessels with a nominal wall thickness of 0.9-1.5 mm. This includes vessels commonly used in cell culture and cell-based assays, such as slides, cell culture dishes and flasks, microtiter well plates, etc. Coverslip-corrected objectives are optimized for use through #1.5 coverslips (thickness approximately 0.17 mm). These objectives have a higher magnification/NA ratio and provide higher resolution compared to LWD objectives.

For additional choices, visit the EVOS® Objectives selection guide
Explore the entire EVOS® line of imaging systems and accessories


规格

For Use With (Equipment):EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Lens Type:Plan Fluorite
Magnification:10X
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:Objective Lens


规格

For Use With (Equipment):EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Lens Type:Plan Fluorite
Magnification:10X
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:Objective Lens


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