产品中心 Products
最新新闻 / News More
1
2019 - 09 - 05
2016年《消失的微生物》一书问世,肠道微生态研究走入大众视野,目前全球范围内针对微生物与肥胖、哮喘、过敏、糖尿病、肿瘤、精神类疾病的研究正逐步开展。一、肠道微生物概况人体是由自身细胞及共生的大量微生物细胞所共同组成的复杂共生生命体。目前研究认为人体肠道内聚集的微生物数目可达1012~1014个,是人体自身细胞数目的10倍,微生物包含的基因数目超过987万个,人类自身基因数只有2万个左右,是人体自身基因数目的几百倍,这些后天获得的共生菌群及其所携带的遗传及分子信息即可称为微生物组。(一)人体肠道微生物是如何建立的?有研究表明,人体在出生成长过程中,主要在两个重要的环节、以两种不同的方式实现对肠道菌群的塑造。第一个环节是在分娩过程,婴儿会从母亲产道获得健康的肠道菌群,剖腹产和孕期抗生素则会改变正常婴儿菌群的建立。另一个环节则是出生后的哺乳及断奶后的膳食干预。在女性乳腺中存在着乳酸菌等系列微生物,这些微生物在哺乳过程中进入并定植于婴儿肠道。随着哺乳期的结束,日趋丰富的膳食外源营养物质则长期调节着人体肠道微生物中的的变化。(二)肠道微生物对人体健康有何影响?肠道菌群与人体互利共生,依靠人体没有消化的食物残渣和肠道分泌的黏液和脱落的死细胞作为营养来维持很高的种群水平。活跃生长的肠道菌群会产生大量的活性物质,同时包括短链脂肪酸、维生素和抗氧化等有益健康的产物,以及神经毒素、致癌物质和免疫毒素...
2
2021 - 05 - 31
2021年05月30日讯 /生物谷BIOON/ --目前,国外新冠肺炎疫情仍在迅速蔓延。根据百度《新型冠状病毒肺炎疫情实时大数据报告》,截止2021年05月30日19时,全球累计确诊超过1.7亿(1.7068亿)例,死亡超过354.9万例。近日,辉瑞(Pfizer)与合作伙伴BioNTech联合宣布,其COVID-19 mRNA疫苗Comirnaty(BNT162b2)在欧盟的有条件营销授权(CMA)已扩大至纳入12-15岁的青少年。在此之前,欧洲药品管理局(EMA)人用医药产品委员会(CHMP)发布积极审查意见,推荐批准Comirnaty用于这一年龄组人群。此次Comirnaty CMA适应症扩展,在欧盟所有27个成员国均有效。Comirnaty是第一个在欧盟获得授权的COVID-19疫苗,也是第一个将其CMA扩展到青少年的疫苗。Comirnaty在欧盟成员国的分发和接种,将继续根据欧盟确定的人口和各个国家的指南来实施。在美国方面,今年5月10日,FDA批准扩大Comirnaty的紧急使用授权(EUA),纳入12-15岁青少年群体。值得一提的是,Comirnaty是在美国被批准用于这一年龄组的首个COVID-19疫苗。此前,FDA已授予Comirnaty用于≥16岁人群进行主动免疫的EUA。BioNTech首席执行官兼联合创始人Ugur Sahin医学博士表示:“今天,我们在欧盟...
3
2018 - 07 - 05
doi.org/10.1038/s41586-018-0162-7基于20年的深入研究,得克萨斯大学西南医学中心(UT Southwestern)自噬研究中心的主任Beth Levine和团队已经明确:细胞自噬可以延长寿命、改善健康。他们以小鼠为模型发现,自噬水平提高的小鼠寿命更长、更健康。“具体来说,它们的寿命延长了约10%,且不太可能发生与年龄相关的自发性癌症、心脏病等疾病。”Beth Levine表示道。细胞自噬自噬是一种保护机制。当细胞内出现衰老的蛋白质、损坏的细胞器等废弃物时,自噬囊泡会将它们包裹并送至溶酶体中进行降解并得以循环利用,从而确保细胞本身的代谢需求和某些细胞器的更新。细胞自噬过程(图片来源:华威大学)20年前,Beth Levine和同事发现了自噬生物学过程中的一个关键基因beclin 1。他们还发现,自噬对于健康而言必不可少,例如预防神经衰退性疾病、对抗癌症和感染。2003年,Beth Levine团队证实,自噬关联的基因机制对于长寿突变线虫(long-lived mutant roundworms)的寿命延长至关重要。“从那以后,关于‘自噬是延长寿命的关键机制’的观点尤为火热。” Beth Levine解释道,“随着年龄增长,细胞的自噬能力会下降,这可能会导致衰老。”自噬延长寿命然而,一个关键问题仍然没有得到解答:增强自噬水平是否有益于哺乳动物的健康?换句...
联系我们
北京照生行仪器设备有限公司
电话:021-64396663
邮箱:coco-cs@ulab360.net
地址:上海市浦东新区康桥路787号中天科技商务园5号楼159单元(近康桥路-锦绣路口)
产品名称:

EVOS™ Light Cube, DAPI

上市日期: 2019-04-12
产品类别: EVOS

规格

Excitation⁄Emission (nm):Ex: 357/44 Em: 447/60
For Use With (Equipment):Countess® II FL Automated Cell Counter, EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:LED Light Cube


  • 产品描述
  • 产品功能
  • 产品参数

描述

All EVOS® fluorescence imaging systems and the Countess® II FL Automated Cell Counter contain our unique, proprietary LED light cubes. This world-leading light engine outputs remarkable intensity over a short light path that delivers superior fluorophore excitation. Each cube contains an LED, condensing optics, and hard-coated filters. EVOS® light cubes are user-changeable and automatically recognized by the system. The DAPI light cube is ideal for use with Acridine, Alexa Fluor® 350, DAPI, Hoechst, NucBlue®, MarinaBlue™, Pacific Blue™ and other fluorophores with excitation and emission maxima near 357 and 447 nm.

EVOS® light cubes offers you these important advantages:

• A shorter light path that affords superior detection of fluorescent signals
• Continuous illumination that enables consistent results
• A 50,000+ hour bulb lifetime that affords lower operating costs
• Adjustable light intensity that helps reduce photobleaching

Revolutionary Light Path
By placing the LED light cube as close as possible to the objective turret, the number of optical elements in the light path is minimized. High-intensity illumination over a short light path increases the efficiency of fluorophore excitation, providing better detection of weak fluorescent signals.

Continuous Light Intensity
Mercury arc lamps can decrease in intensity by 50% in the first 100 hours of operation—plus, images acquired in different sessions cannot be quantitatively compared using mercury illumination without complicated calibrations. Because EVOS® systems have continuous light cube intensity, users can rely on consistent illumination and can compare quantitative results from images acquired on different days. Each light cube contains a precisely matched set of optical components to optimize the position, evenness, and intensity of the light beam. Digitally controlled LED light sources allow adjustment of illumination levels, dramatically improving control over photobleaching.

Less Expensive to Own and Maintain
The LED bulbs on the EVOS® systems are rated for >50,000 hours (~17 years), compared to 300 hours for a typical mercury bulb and 1,500 hours for a metal halide bulb. This translates to savings in the overall upkeep of your instrument.

EVOS® Hard-coated Filter Sets for Higher Transmission Efficiencies
Hard-coated filter sets are more expensive that soft-coated filters, but they have sharper edges and significantly higher transmission efficiencies that typically result in >25% more light transmission than traditional soft-coated filters. With the EVOS® systems' hard-coated filter sets, your light cubes cost less over time. Plus, you will have brighter fluorescence, higher transmission efficiencies, the ability to detect faint fluorescence signals, and better signal-to-noise ratios. 


规格

Excitation⁄Emission (nm):Ex: 357/44 Em: 447/60
For Use With (Equipment):Countess® II FL Automated Cell Counter, EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:LED Light Cube


规格

Excitation⁄Emission (nm):Ex: 357/44 Em: 447/60
For Use With (Equipment):Countess® II FL Automated Cell Counter, EVOS® FL Auto Imaging System, EVOS® FL Color Imaging System, EVOS® FL Imaging System
Product Line:EVOS®
Product Size:1 each
Quantity:1 each
Type:LED Light Cube


地址:中国·上海·浦东区-浦东新区康桥路787号5号楼159室
电话:021-64396663
Copyright@ 2015-2016 北京照生行仪器设备有限公司
传真:+86 0755-2788 8009
邮编:330520