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科学家发现精神分裂相关基因位点
科学家发现精神分裂相关基因位点
2019 - 02 - 01
复旦大学类脑智能科学与技术研究院冯建峰团队对来自英美等 6 个国家、20 余所研究机构超过 1 万例影像遗传学数据进行计算分析，通过全脑全基因组范围的 “广泛搜索”，发现与青春期大脑壳核体积相关的基因位点同时也是精神分裂症的风险位点。该成果近日发表于《美国医学会杂志—精神病学卷》。“这项研究证明青春期大脑壳核体积异常和精神分裂症致病风险高度相关。” 冯建峰表示，该发现有望帮助科学家揭示精神分裂症发病机制，为临床症状出现之前的超前干预研究提供新思路。精神疾病防治是当今世界各国面临的共同难题。据报道，在中国，精神疾病已超过心脑血管疾病和恶性肿瘤，成为医疗体系的最大负担。“大脑在不同年龄受不同遗传信息影响，此前的研究未严格控制这一混杂因素，导致重要的遗传信号被‘淹没’。” 论文第一作者、复旦大学类脑智能科学与技术研究院副研究员罗强告诉《中国科学报》，研究团队选取了 14 岁健康青少年脑结构影像数据，同时突破了传统的解剖学脑区划分限制，在全脑全基因组范围内开展无偏的探索性研究，首次找到了青少年大脑结构与基因位点之间最为显著的关联关系。同时针对该结果，研究人员进一步开展了孟德尔随机化分析，发现了一条基因—大脑—精神分裂症的新通路。“这项研究的突破主要基于对来自全球范围的多中心影像遗传学数据进行计算分析，这些全维度标准化大数据的获取，得益于多年来我们在全世界范围内深入开展的国际合作研究。” 冯...
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研究发现不健康饮食导致大脑退化
研究发现不健康饮食导致大脑退化
2019 - 06 - 18
和50年前相比，现在人们日常卡路里摄入更多，平均每天高出650大卡，相当于每天多吃了一顿有汉堡、薯条和可乐的套餐，约占男性和女性每日所需食物能量的1/4和1/3。这些多余的卡路里不仅体现在越来越多人圆滚的腰围上，根据澳大利亚国立大学（Australian National University，ANU）的专家提醒，更会对我们的大脑带来“毁灭性”的影响。ANU团队的最新研究显示，由于不健康生活方式，大脑功能衰退可能比我们想象得更早。研究结果近日发表在Frontiers in Neuroendocrinology。根据世界卫生组织的数据，全球约有39%的成人超重，13%的成人肥胖。作为超重和肥胖的常见健康后果之一，2型糖尿病在2030年将影响约10%的成人。众所周知，2型糖尿病与大脑健康受损、认知功能退化有关，神经损伤也是糖尿病的并发症之一。那么，在还没有出现高血糖等符合糖尿病诊断的症状时，神经退行性病变和认知障碍是否也已经处于病理过程中了？又与哪些导致血糖变化的因素有关？研究团队回顾了近200项相关的国际研究，结果表明，即便是非糖尿病人群，由于血糖偏高和肥胖而导致的神经病变也在非常早期就开始了，并且从那时起就开始影响大脑健康和认知功能。比如，一项涉及澳大利亚超过7000人的PATH研究显示，哪怕血糖值尚且在正常范围内，但血糖偏高的人群，大脑中海马和杏仁核普遍萎缩更多，4年内体积约缩小...
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照生行——上海慕尼黑生化分析展完美收官
照生行——上海慕尼黑生化分析展完美收官
2018 - 11 - 08
2018年10月31日-11月2日，北京照生行仪器设备有限公司在上海新国际展览中心E2-2380馆亮相2018慕尼黑上海生化分析展。                                                                                   目前，作为美国Labconco公司在中国的独家代理商，为全国范围内的客户提供Labconco公司的全线产品——冷冻干燥系统、生物安全柜、洗瓶机、离心浓缩仪、样品快速蒸发系统、通风橱、动物柜、手套箱等。金牌级别的销售为您保“价”护航。此次展会，小佑很荣幸的去到上海这座魔都支持展会活动。在慕尼黑生化分析展开始前，小佑给大家展示过我们展台的效果图，今天小佑带大家欣赏我们展台搭建的实体效果噻！就说美不美？展会期间我们将冷冻干燥系统、离心浓缩系统、生物安全柜和洗瓶机的系列产品携带于展会。让更多的观...
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EVOS™ 50X Oil Objective, achromat, coverslip-corrected
产品名称： EVOS™ 50X Oil Objective, achromat, coverslip-corrected
型号：
时间： 2019 - 04 - 15
描述This achromat objective is ideal for general applications. This is a coverslip-corrected objective that is optimized for imaging through #1.5 coverslips. All EVOS® objectives offer outstanding optical performance from visible light to near infrared light. The extensive choice of objectives satisfies needs across the spectrum of magnifications and optical specifications.Additional characteristics of this EVOS® objective:• Magnification: 50X• Numerical Aperture: 0.95• Working Distance:...
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EVOS™ M7000 Imaging System
产品名称： EVOS™ M7000 Imaging System
型号：
时间： 2019 - 04 - 15
描述The EVOS M7000 Imaging System is a high-performance, fully automated, inverted, multi-channel fluorescence and transmitted light imaging system. It was developed to meet today’s expectations for image quality, user interface interactions, data generation speed and flexibility, and end-user value. The powerful and time-saving acquisition tools with enhanced autofocus algorithms and automated routines for microwell plate assays, time-lapse live cell imaging, area scanning in time lapse and Z-sta...
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EVOS™ FL Imaging System
产品名称： EVOS™ FL Imaging System
型号：
时间： 2019 - 04 - 15
描述The EVOS® FL Imaging System is a fully integrated, digital, inverted imaging system for four-color fluorescence and transmitted-light applications. It is powerful, yet easy-to-use and delivers high-definition images with exceptional convenience. The unique light cubes, sensitive camera, and precision-engineered optical system make the EVOS® FL system ideal for both demanding and routine fluorescence imaging applications.The EVOS® FL Imaging System offers you these important ad...
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EVOS™ Onstage Master Plate
产品名称： EVOS™ Onstage Master Plate
型号：
时间： 2019 - 04 - 15
描述The EVOS® Onstage Master Plate is part of the EVOS® Onstage Incubator and holds the EVOS® Onstage Vessel Holder. The EVOS® Onstage Incubator is an environmental chamber designed specifically for use with the EVOS® FL Auto Imaging System. This master plate plus vessel holder design, with vessel holders available that accommodate various types of cell culture vessels, provides flexibility in your approach to extended time-lapse imaging experiments under precisely co...
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EVOS™ Onstage Vessel Holder, two 25-mL flasks
产品名称： EVOS™ Onstage Vessel Holder, two 25-mL flasks
型号：
时间： 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates two 25-mL T-flasks. With ...
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EVOS™ Onstage Vessel Holder, multi-well plates
产品名称： EVOS™ Onstage Vessel Holder, multi-well plates
型号：
时间： 2019 - 04 - 15
描述EVOS® Onstage vessel holders maximize your choice of cell culture vessels when conducting time-lapse imaging experiments using the EVOS® FL Auto Imaging System equipped with an EVOS® Onstage Incubator. EVOS® Onstage vessel holders allow a perfect fit of your micro-well plates or cell culture flasks/dishes to the master plate of the EVOS® Onstage Incubator for increased precision in sample alignment. This particular vessel holder accommodates multi-well plates (dimensi...
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EVOS™ Vessel Holder for Automated Stage, two 25 x 75 mm slides
产品名称： EVOS™ Vessel Holder for Automated Stage, two 25 x 75 mm slides
型号：
时间： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder securely holds two 25 x 75 mm standard or chamber microscope slides and is specific for the automated stage of the EVOS® FL Auto Imaging System. It is just one of many easy-to-change vessel holders and stage plates available for this instrument plat...
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EVOS™Vessel Holder, Greiner/BD T-25 flask
产品名称： EVOS™Vessel Holder, Greiner/BD T-25 flask
型号：
时间： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Greiner/BD T-25 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ...
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EVOS™ Vessel Holder, universal
产品名称： EVOS™ Vessel Holder, universal
型号：
时间： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder has a 25.4 mm opening and accommodates most vessel types. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samp...
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EVOS™ Vessel Holder, Greiner T-75 flask
产品名称： EVOS™ Vessel Holder, Greiner T-75 flask
型号：
时间： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Greiner T-75 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ves...
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EVOS™ Vessel Holder, Hemocytometer
产品名称： EVOS™ Vessel Holder, Hemocytometer
型号：
时间： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates a hemocytometer. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of vessel hol...
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EVOS™ Vessel Holder, Nunc™ T-75 flask
产品名称： EVOS™ Vessel Holder, Nunc™ T-75 flask
型号：
时间： 2019 - 04 - 15
描述EVOS® vessel holders allow a perfect fit of your microscope slide, cell culture flask or dish, or micro-well plate to the stage of the EVOS® imaging systems for increased precision in sample alignment. This particular vessel holder accommodates one Nunc® T-75 flask. It is just one of many easy-to-change vessel holders and stage plates available for this instrument platform. With a snug and secure fit, yet readily switched, these accessories make imaging samples in a range of ...
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